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HSPB1, HSPB6, HSPB7 and HSPB8 Protect against RhoA GTPase-Induced Remodeling in Tachypaced Atrial Myocytes

BACKGROUND: We previously demonstrated the small heat shock protein, HSPB1, to prevent tachycardia remodeling in in vitro and in vivo models for Atrial Fibrillation (AF). To gain insight into its mechanism of action, we examined the protective effect of all 10 members of the HSPB family on tachycard...

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Detalles Bibliográficos
Autores principales: Ke, Lei, Meijering, Roelien A. M., Hoogstra-Berends, Femke, Mackovicova, Katarina, Vos, Michel J., Van Gelder, Isabelle C., Henning, Robert H., Kampinga, Harm H., Brundel, Bianca J. J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123278/
https://www.ncbi.nlm.nih.gov/pubmed/21731611
http://dx.doi.org/10.1371/journal.pone.0020395