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Intramuscular immunization of mice with live influenza virus is more immunogenic and offers greater protection than immunization with inactivated virus
BACKGROUND: Influenza virus continues to cause significant hospitalization rates in infants and young children. A 2-dose regime of trivalent inactivated vaccine is required to generate protective levels of hemagglutination inhibiting (HAI) antibodies. A vaccine preparation with enhanced immunogenici...
Autores principales: | Harris, Katie, Ream, Rebecca, Gao, Jin, Eichelberger, Maryna C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123286/ https://www.ncbi.nlm.nih.gov/pubmed/21600020 http://dx.doi.org/10.1186/1743-422X-8-251 |
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