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Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML

As the defining feature of Acute Myeloid Leukemia (AML) is a maturation arrest, a highly desirable therapeutic strategy is to induce leukemic cell maturation. This therapeutic strategy has the potential of avoiding the significant side effects that occur with the traditional AML therapeutics. We ide...

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Detalles Bibliográficos
Autores principales: Gupta, Kalpana, Chakrabarti, Amitabha, Rana, Sonia, Ramdeo, Ritu, Roth, Bryan L., Agarwal, Munna L., Tse, William, Agarwal, Mukesh K., Wald, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123298/
https://www.ncbi.nlm.nih.gov/pubmed/21731671
http://dx.doi.org/10.1371/journal.pone.0021203