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Securinine, a Myeloid Differentiation Agent with Therapeutic Potential for AML
As the defining feature of Acute Myeloid Leukemia (AML) is a maturation arrest, a highly desirable therapeutic strategy is to induce leukemic cell maturation. This therapeutic strategy has the potential of avoiding the significant side effects that occur with the traditional AML therapeutics. We ide...
Autores principales: | Gupta, Kalpana, Chakrabarti, Amitabha, Rana, Sonia, Ramdeo, Ritu, Roth, Bryan L., Agarwal, Munna L., Tse, William, Agarwal, Mukesh K., Wald, David N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123298/ https://www.ncbi.nlm.nih.gov/pubmed/21731671 http://dx.doi.org/10.1371/journal.pone.0021203 |
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