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Role of TMPRSS2-ERG Gene Fusion in Negative Regulation of PSMA Expression

Prostate specific membrane antigen (PSMA) is overexpressed in prostatic adenocarcinoma (CaP), and its expression is negatively regulated by androgen stimulation. However, it is still unclear which factors are involved in this downregulation. TMPRSS2-ERG fusion is the most common known gene rearrange...

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Detalles Bibliográficos
Autores principales: Yin, Lihong, Rao, Pravin, Elson, Paul, Wang, Jianghua, Ittmann, Michael, Heston, Warren D. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123299/
https://www.ncbi.nlm.nih.gov/pubmed/21731703
http://dx.doi.org/10.1371/journal.pone.0021319