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The novel chemokine receptor CXCR7 regulates trans-endothelial migration of cancer cells

BACKGROUND: Migration of metastatic tumor cells from the bloodstream into lymph nodes is thought to be facilitated by expression of the chemokine receptors CCR7, CXCR4 and, for B cell-derived tumors, CXCR5. Expression of their respective chemokine ligands (CCL19, CCL21, CXCL12 and CXCL13) by endothe...

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Detalles Bibliográficos
Autores principales: Zabel, Brian A, Lewén, Susanna, Berahovich, Robert D, Jaén, Juan C, Schall, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123309/
https://www.ncbi.nlm.nih.gov/pubmed/21672222
http://dx.doi.org/10.1186/1476-4598-10-73