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Genes in the terminal regions of orthopoxvirus genomes experience adaptive molecular evolution

BACKGROUND: Orthopoxviruses are dsDNA viruses with large genomes, some encoding over 200 genes. Genes essential for viral replication are located in the center of the linear genome and genes encoding host response modifiers and other host interacting proteins are located in the terminal regions. The...

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Detalles Bibliográficos
Autores principales: Esteban, David J, Hutchinson, Anne P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123329/
https://www.ncbi.nlm.nih.gov/pubmed/21605412
http://dx.doi.org/10.1186/1471-2164-12-261