Functional Analysis of Conserved Non-Coding Regions Around the Short Stature hox Gene (shox) in Whole Zebrafish Embryos

BACKGROUND: Mutations in the SHOX gene are responsible for Leri-Weill Dyschondrosteosis, a disorder characterised by mesomelic limb shortening. Recent investigations into regulatory elements surrounding SHOX have shown that deletions of conserved non-coding elements (CNEs) downstream of the SHOX gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Kenyon, Emma J., McEwen, Gayle K., Callaway, Heather, Elgar, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123344/
https://www.ncbi.nlm.nih.gov/pubmed/21731768
http://dx.doi.org/10.1371/journal.pone.0021498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123344/
https://www.ncbi.nlm.nih.gov/pubmed/21731768
http://dx.doi.org/10.1371/journal.pone.0021498

Ejemplares similares