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Carcinoma Matrix Controls Resistance to Cisplatin through Talin Regulation of NF-kB

Extracellular matrix factors within the tumor microenvironment that control resistance to chemotherapeutics are poorly understood. This study focused on understanding matrix adhesion pathways that control the oral carcinoma response to cisplatin. Our studies revealed that adhesion of HN12 and JHU012...

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Detalles Bibliográficos
Autores principales: Eberle, Karen E., Sansing, Hope A., Szaniszlo, Peter, Resto, Vicente A., Berrier, Allison L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123362/
https://www.ncbi.nlm.nih.gov/pubmed/21720550
http://dx.doi.org/10.1371/journal.pone.0021496