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P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus

BACKGROUND: The release of tumor necrosis factor-α (TNF-α) appears depend on the P2X7 receptor, a purinergic receptor. In the present study, we addressed the question of whether P2X7 receptor-mediated TNF-α regulation is involved in pathogenesis and outcome of status epilepticus (SE). METHODS: SE wa...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Ryu, Hea Jin, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123566/
https://www.ncbi.nlm.nih.gov/pubmed/21631954
http://dx.doi.org/10.1186/1742-2094-8-62