Codon usage in vertebrates is associated with a low risk of acquiring nonsense mutations

BACKGROUND: Codon usage in genomes is biased towards specific subsets of codons. Codon usage bias affects translational speed and accuracy, and it is associated with the tRNA levels and the GC content of the genome. Spontaneous mutations drive genomes to a low GC content. Active cellular processes a...

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Detalles Bibliográficos
Autores principales: Schmid, Pirmin, Flegel, Willy A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123582/
https://www.ncbi.nlm.nih.gov/pubmed/21651781
http://dx.doi.org/10.1186/1479-5876-9-87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123582/
https://www.ncbi.nlm.nih.gov/pubmed/21651781
http://dx.doi.org/10.1186/1479-5876-9-87

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