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Intracisternal administration of NR2 subunit antagonists attenuates the nociceptive behavior and p-p38 MAPK expression produced by compression of the trigeminal nerve root

BACKGROUND: We investigated the role of the central NMDA receptor NR2 subunits in the modulation of nociceptive behavior and p-p38 MAPK expression in a rat model with compression of the trigeminal nerve root. To address this possibility, changes in air-puff thresholds and pin-prick scores were deter...

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Detalles Bibliográficos
Autores principales: Jeon, Hye J, Han, Seung R, Lim, Koang H, Won, Kyoung A, Bae, Yong C, Ahn, Dong K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123587/
https://www.ncbi.nlm.nih.gov/pubmed/21651766
http://dx.doi.org/10.1186/1744-8069-7-46