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Polymorphism of Plasmodium falciparum Na(+)/H(+ )exchanger is indicative of a low in vitro quinine susceptibility in isolates from Viet Nam

BACKGROUND: The Plasmodium falciparum NA+/H+ exchanger (pfnhe1, gene PF13_0019) has recently been proposed to influence quinine (QN) susceptibility. However, its contribution to QN resistance seems to vary geographically depending on the genetic background of the parasites. Here, the role of this ge...

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Detalles Bibliográficos
Autores principales: Sinou, Véronique, Quang, Le Hong, Pelleau, Stéphane, Huong, Vu Nhu, Huong, Nguyen Thu, Tai, Le Minh, Bertaux, Lionel, Desbordes, Marc, Latour, Christine, Long, Lai Quang, Thanh, Nguyen Xuan, Parzy, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123604/
https://www.ncbi.nlm.nih.gov/pubmed/21669011
http://dx.doi.org/10.1186/1475-2875-10-164