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New methods to measure residues coevolution in proteins

BACKGROUND: The covariation of two sites in a protein is often used as the degree of their coevolution. To quantify the covariation many methods have been developed and most of them are based on residues position-specific frequencies by using the mutual information (MI) model. RESULTS: In the paper,...

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Detalles Bibliográficos
Autores principales: Gao, Hongyun, Dou, Yongchao, Yang, Jialiang, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123609/
https://www.ncbi.nlm.nih.gov/pubmed/21612664
http://dx.doi.org/10.1186/1471-2105-12-206