The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors

BACKGROUND: Current large-scale cancer sequencing projects have identified large numbers of somatic mutations covering an increasing number of different cancer tissues and patients. However, the characterization of these mutations at the structural and functional level remains a challenge. RESULTS:...

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Detalles Bibliográficos
Autores principales: Stehr, Henning, Jang, Seon-Hi J, Duarte, José M, Wierling, Christoph, Lehrach, Hans, Lappe, Michael, Lange, Bodo MH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123651/
https://www.ncbi.nlm.nih.gov/pubmed/21575214
http://dx.doi.org/10.1186/1476-4598-10-54

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123651/
https://www.ncbi.nlm.nih.gov/pubmed/21575214
http://dx.doi.org/10.1186/1476-4598-10-54

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