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Phase II study of the combination carboplatin plus celecoxib in heavily pre-treated recurrent ovarian cancer patients

BACKGROUND: Cyclooxygenase-2 overexpression is associated with poor outcome and resistance to platinum-based chemotherapy in ovarian cancer. We evaluated the antitumor activity and safety of the combination carboplatin plus the COX-2 inhibitor celecoxib in recurrent heavily-treated OC patients. METH...

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Detalles Bibliográficos
Autores principales: Legge, Francesco, Paglia, Amelia, D'Asta, Marco, Fuoco, Gilda, Scambia, Giovanni, Ferrandina, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123659/
https://www.ncbi.nlm.nih.gov/pubmed/21627839
http://dx.doi.org/10.1186/1471-2407-11-214