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Phase II study of the combination carboplatin plus celecoxib in heavily pre-treated recurrent ovarian cancer patients
BACKGROUND: Cyclooxygenase-2 overexpression is associated with poor outcome and resistance to platinum-based chemotherapy in ovarian cancer. We evaluated the antitumor activity and safety of the combination carboplatin plus the COX-2 inhibitor celecoxib in recurrent heavily-treated OC patients. METH...
Autores principales: | Legge, Francesco, Paglia, Amelia, D'Asta, Marco, Fuoco, Gilda, Scambia, Giovanni, Ferrandina, Gabriella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123659/ https://www.ncbi.nlm.nih.gov/pubmed/21627839 http://dx.doi.org/10.1186/1471-2407-11-214 |
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