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Assessment of Glucagon-Like Peptide-1 Analogue and Renin Inhibitor on the Binding and Regulation of GLP-1 Receptor in Type 1 Diabetic Rat Hearts

This study focuses on the effects of long-term renin-angiotensin system suppression and/or incretin mimetic therapies on the regulation and binding affinity of GLP-1 to its receptor in the coronary endothelium (CE) and cardiomyocytes (CMs) of type 1 diabetic male Sprague-Dawley rats. The groups asse...

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Detalles Bibliográficos
Autores principales: Artinian, Shushan B., Al Lafi, Sawsan M., Boutary, Suzan S., Bitar, Khalil M., Zwainy, Nadine S., Bikhazi, Anwar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124137/
https://www.ncbi.nlm.nih.gov/pubmed/21747829
http://dx.doi.org/10.1155/2011/489708