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New formulation of an old drug in hypertension treatment: the sustained release of captopril from cyclodextrin nanoparticles
Captopril (CAP) was the first angiotensin I-converting enzyme (ACE) inhibitor to be developed and is widely used in hypertension treatment. On the other hand, cyclodextrins (CDs) are cyclic oligosaccharides whose cone-shaped cavity allows formation of noncovalent inclusion complexes with appropriate...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124386/ https://www.ncbi.nlm.nih.gov/pubmed/21720512 http://dx.doi.org/10.2147/IJN.S18999 |