New formulation of an old drug in hypertension treatment: the sustained release of captopril from cyclodextrin nanoparticles

Captopril (CAP) was the first angiotensin I-converting enzyme (ACE) inhibitor to be developed and is widely used in hypertension treatment. On the other hand, cyclodextrins (CDs) are cyclic oligosaccharides whose cone-shaped cavity allows formation of noncovalent inclusion complexes with appropriate...

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Detalles Bibliográficos
Autores principales: de Azevedo, Mariangela de Burgos M, Tasic, Ljubica, Fattori, Juliana, Rodrigues, Fábio HS, Cantos, Fabiana C, Ribeiro, Leandro P, de Paula, Vanice, Ianzer, Danielle, Santos, Robson AS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124386/
https://www.ncbi.nlm.nih.gov/pubmed/21720512
http://dx.doi.org/10.2147/IJN.S18999

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