Molecular Modelling of the Emergence of Azole Resistance in Mycosphaerella graminicola

A structural rationale for recent emergence of azole (imidazole and triazole) resistance associated with CYP51 mutations in the wheat pathogen Mycosphaerella graminicola is presented, attained by homology modelling of the wild type protein and 13 variant proteins. The novel molecular models of M. gr...

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Detalles Bibliográficos
Autores principales: Mullins, Jonathan G. L., Parker, Josie E., Cools, Hans J., Togawa, Roberto C., Lucas, John A., Fraaije, Bart A., Kelly, Diane E., Kelly, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124474/
https://www.ncbi.nlm.nih.gov/pubmed/21738598
http://dx.doi.org/10.1371/journal.pone.0020973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124474/
https://www.ncbi.nlm.nih.gov/pubmed/21738598
http://dx.doi.org/10.1371/journal.pone.0020973

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