B Vitamins, Methionine and Alcohol Intake and Risk of Colon Cancer in Relation to BRAF Mutation and CpG Island Methylator Phenotype (CIMP)

BACKGROUND: One-carbon metabolism appears to play an important role in DNA methylation reaction. Evidence suggests that a low intake of B vitamins or high alcohol consumption increases colorectal cancer risk. How one-carbon nutrients affect the CpG island methylator phenotype (CIMP) or BRAF mutation...

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Detalles Bibliográficos
Autores principales: Schernhammer, Eva S., Giovannucci, Edward, Baba, Yoshifumi, Fuchs, Charles S., Ogino, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124479/
https://www.ncbi.nlm.nih.gov/pubmed/21738611
http://dx.doi.org/10.1371/journal.pone.0021102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124479/
https://www.ncbi.nlm.nih.gov/pubmed/21738611
http://dx.doi.org/10.1371/journal.pone.0021102

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