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Fisetin Lowers Methylglyoxal Dependent Protein Glycation and Limits the Complications of Diabetes

The elevated glycation of macromolecules by the reactive dicarbonyl and α-oxoaldehyde methylglyoxal (MG) has been associated with diabetes and its complications. We have identified a rare flavone, fisetin, which increases the level and activity of glyoxalase 1, the enzyme required for the removal of...

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Detalles Bibliográficos
Autores principales: Maher, Pamela, Dargusch, Richard, Ehren, Jennifer L., Okada, Shinichi, Sharma, Kumar, Schubert, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124487/
https://www.ncbi.nlm.nih.gov/pubmed/21738623
http://dx.doi.org/10.1371/journal.pone.0021226

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