Exceptional Hyperthyroidism and a Role for both Major Histocompatibility Class I and Class II Genes in a Murine Model of Graves' Disease

Autoimmune hyperthyroidism, Graves' disease, can be induced by immunizing susceptible strains of mice with adenovirus encoding the human thyrotropin receptor (TSHR) or its A-subunit. Studies in two small families of recombinant inbred strains showed that susceptibility to developing TSHR antibo...

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Detalles Bibliográficos
Autores principales: McLachlan, Sandra M., Aliesky, Holly A., Chen, Chun-Rong, Williams, Robert W., Rapoport, Basil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124500/
https://www.ncbi.nlm.nih.gov/pubmed/21738647
http://dx.doi.org/10.1371/journal.pone.0021378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124500/
https://www.ncbi.nlm.nih.gov/pubmed/21738647
http://dx.doi.org/10.1371/journal.pone.0021378

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