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SWI/SNF and Asf1 Independently Promote Derepression of the DNA Damage Response Genes under Conditions of Replication Stress

The histone chaperone Asf1 and the chromatin remodeler SWI/SNF have been separately implicated in derepression of the DNA damage response (DDR) genes in yeast cells treated with genotoxins that cause replication interference. Using genetic and biochemical approaches, we have tested if derepression o...

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Detalles Bibliográficos
Autores principales: Minard, Laura V., Lin, Ling-ju, Schultz, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124541/
https://www.ncbi.nlm.nih.gov/pubmed/21738741
http://dx.doi.org/10.1371/journal.pone.0021633