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Effector and Naturally Occurring Regulatory T Cells Display No Abnormalities in Activation Induced Cell Death in NOD Mice

BACKGROUND: Disturbed peripheral negative regulation might contribute to evolution of autoimmune insulitis in type 1 diabetes. This study evaluates the sensitivity of naïve/effector (Teff) and regulatory T cells (Treg) to activation-induced cell death mediated by Fas cross-linking in NOD and wild-ty...

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Detalles Bibliográficos
Autores principales: Kaminitz, Ayelet, Yolcu, Esma S., Askenasy, Enosh M., Stein, Jerry, Yaniv, Isaac, Shirwan, Haval, Askenasy, Nadir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124542/
https://www.ncbi.nlm.nih.gov/pubmed/21738739
http://dx.doi.org/10.1371/journal.pone.0021630