Refined human artificial chromosome vectors for gene therapy and animal transgenesis

Human artificial chromosomes (HACs) have several advantages as gene therapy vectors, including stable episomal maintenance, and the ability to carry large gene inserts. We previously developed HAC vectors from the normal human chromosomes using a chromosome engineering technique. However, endogenous...

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Detalles Bibliográficos
Autores principales: Kazuki, Y, Hoshiya, H, Takiguchi, M, Abe, S, Iida, Y, Osaki, M, Katoh, M, Hiratsuka, M, Shirayoshi, Y, Hiramatsu, K, Ueno, E, Kajitani, N, Yoshino, T, Kazuki, K, Ishihara, C, Takehara, S, Tsuji, S, Ejima, F, Toyoda, A, Sakaki, Y, Larionov, V, Kouprina, N, Oshimura, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125098/
https://www.ncbi.nlm.nih.gov/pubmed/21085194
http://dx.doi.org/10.1038/gt.2010.147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125098/
https://www.ncbi.nlm.nih.gov/pubmed/21085194
http://dx.doi.org/10.1038/gt.2010.147

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