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Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-κB pathways in intestinal epithelial cells

The polymeric immunoglobulin receptor (pIgR) transports IgA antibodies across intestinal epithelial cells (IECs). Expression of pIgR is upregulated by proinflammatory signaling pathways via activation of nuclear factor-κB (NF-κB). Here, we examined the contributions of the RelA-dependent classical a...

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Detalles Bibliográficos
Autores principales: Bruno, M E C, Frantz, A L, Rogier, E W, Johansen, F-E, Kaetzel, C S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125104/
https://www.ncbi.nlm.nih.gov/pubmed/21451502
http://dx.doi.org/10.1038/mi.2011.8