Synthesis of potential metal-binding group compounds to examine the zinc dependency of the GPI de-N-acetylase metalloenzyme in Trypanosoma brucei

A small zinc-binding group (ZBG) library of deoxy-2-C-branched-monosaccharides, for example, 1,5-anhydroglucitols, consisting of either monodentate ligand binding carboxylic acids or bidentate ligand binding hydroxamic acids, were prepared to assess the zinc affinity of the putative metalloenzyme 2-...

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Detalles Bibliográficos
Autores principales: Abdelwahab, Nuha Z., Urbaniak, Michael D., Ferguson, Michael A.J., Crossman, Arthur T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125106/
https://www.ncbi.nlm.nih.gov/pubmed/21377660
http://dx.doi.org/10.1016/j.carres.2011.02.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125106/
https://www.ncbi.nlm.nih.gov/pubmed/21377660
http://dx.doi.org/10.1016/j.carres.2011.02.004

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