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Evidence for a Peak Shift in a Humoral Response to Helminths: Age Profiles of IgE in the Shuar of Ecuador, the Tsimane of Bolivia, and the U.S. NHANES

BACKGROUND: The peak shift model predicts that the age-profile of a pathogen's prevalence depends upon its transmission rate, peaking earlier in populations with higher transmission and declining as partial immunity is acquired. Helminth infections are associated with increased immunoglobulin E...

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Detalles Bibliográficos
Autores principales: Blackwell, Aaron D., Gurven, Michael D., Sugiyama, Lawrence S., Madimenos, Felicia C., Liebert, Melissa A., Martin, Melanie A., Kaplan, Hillard S., Snodgrass, J. Josh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125146/
https://www.ncbi.nlm.nih.gov/pubmed/21738813
http://dx.doi.org/10.1371/journal.pntd.0001218