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Large-Scale Assessment of the Zebrafish Embryo as a Possible Predictive Model in Toxicity Testing
BACKGROUND: In the drug discovery pipeline, safety pharmacology is a major issue. The zebrafish has been proposed as a model that can bridge the gap in this field between cell assays (which are cost-effective, but low in data content) and rodent assays (which are high in data content, but less cost-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125172/ https://www.ncbi.nlm.nih.gov/pubmed/21738604 http://dx.doi.org/10.1371/journal.pone.0021076 |