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Ultrastructural changes of the intracellular surfactant pool in a rat model of lung transplantation-related events

BACKGROUND: Ischemia/reperfusion (I/R) injury, involved in primary graft dysfunction following lung transplantation, leads to inactivation of intra-alveolar surfactant which facilitates injury of the blood-air barrier. The alveolar epithelial type II cells (AE2 cells) synthesize, store and secrete s...

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Detalles Bibliográficos
Autores principales: Knudsen, Lars, Waizy, Hazibullah, Fehrenbach, Heinz, Richter, Joachim, Wahlers, Thorsten, Wittwer, Thorsten, Ochs, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125224/
https://www.ncbi.nlm.nih.gov/pubmed/21669009
http://dx.doi.org/10.1186/1465-9921-12-79