Reversal of TGF-β(1 )stimulation of α-smooth muscle actin and extracellular matrix components by cyclic AMP in Dupuytren's - derived fibroblasts

BACKGROUND: Myofibroblasts, a derived subset of fibroblasts especially important in scar formation and wound contraction, have been found at elevated levels in affected Dupuytren's tissues. Transformation of fibroblasts to myofibroblasts is characterized by expression of alpha- smooth muscle ac...

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Detalles Bibliográficos
Autores principales: Satish, Latha, Gallo, Phillip H, Baratz, Mark E, Johnson, Sandra, Kathju, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125251/
https://www.ncbi.nlm.nih.gov/pubmed/21612641
http://dx.doi.org/10.1186/1471-2474-12-113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125251/
https://www.ncbi.nlm.nih.gov/pubmed/21612641
http://dx.doi.org/10.1186/1471-2474-12-113

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