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Normalization and centering of array-based heterologous genome hybridization based on divergent control probes
BACKGROUND: Hybridization of heterologous (non-specific) nucleic acids onto arrays designed for model-organisms has been proposed as a viable genomic resource for estimating sequence variation and gene expression in non-model organisms. However, conventional methods of normalization that assume equi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125262/ https://www.ncbi.nlm.nih.gov/pubmed/21600029 http://dx.doi.org/10.1186/1471-2105-12-183 |