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Antiprogestin mifepristone inhibits the growth of cancer cells of reproductive and non-reproductive origin regardless of progesterone receptor expression

BACKGROUND: Mifepristone (MF) has been largely used in reproductive medicine due to its capacity to modulate the progesterone receptor (PR). The study of MF has been expanded to the field of oncology; yet it remains unclear whether the expression of PR is required for MF to act as an anti-cancer age...

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Detalles Bibliográficos
Autores principales: Tieszen, Chelsea R, Goyeneche, Alicia A, Brandhagen, BreeAnn N, Ortbahn, Casey T, Telleria, Carlos M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125282/
https://www.ncbi.nlm.nih.gov/pubmed/21619605
http://dx.doi.org/10.1186/1471-2407-11-207