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α(1A)-Adrenergic Receptor Induces Activation of Extracellular Signal-Regulated Kinase 1/2 through Endocytic Pathway

G protein-coupled receptors (GPCRs) activate mitogen-activated protein kinases through a number of distinct pathways in cells. Increasing evidence has suggested that endosomal signaling has an important role in receptor signal transduction. Here we investigated the involvement of endocytosis in α(1A...

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Detalles Bibliográficos
Autores principales: Liu, Fei, He, Kangmin, Yang, Xinxing, Xu, Ning, Liang, Zhangyi, Xu, Ming, Zhao, Xinsheng, Han, Qide, Zhang, Youyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125289/
https://www.ncbi.nlm.nih.gov/pubmed/21738688
http://dx.doi.org/10.1371/journal.pone.0021520