High DNA Methylation Pattern Intratumoral Diversity Implies Weak Selection in Many Human Colorectal Cancers

BACKGROUND: It is possible to infer the past of populations by comparing genomes between individuals. In general, older populations have more genomic diversity than younger populations. The force of selection can also be inferred from population diversity. If selection is strong and frequently elimi...

Descripción completa

Detalles Bibliográficos
Autores principales: Siegmund, Kimberly D., Marjoram, Paul, Tavaré, Simon, Shibata, Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125304/
https://www.ncbi.nlm.nih.gov/pubmed/21738754
http://dx.doi.org/10.1371/journal.pone.0021657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125304/
https://www.ncbi.nlm.nih.gov/pubmed/21738754
http://dx.doi.org/10.1371/journal.pone.0021657

Ejemplares similares