Study of the IgG endoglycosidase EndoS in group A streptococcal phagocyte resistance and virulence

BACKGROUND: The secreted enzyme EndoS, an endoglycosidase from Streptococcus pyogenes, hydrolyzes the N-linked glycan of the constant region of immunoglobulin G (IgG) heavy chain and renders the antibody unable to interact with Fc receptors and elicit effector functions. In this study we couple targ...

Descripción completa

Detalles Bibliográficos
Autores principales: Sjögren, Jonathan, Okumura, Cheryl YM, Collin, Mattias, Nizet, Victor, Hollands, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125321/
https://www.ncbi.nlm.nih.gov/pubmed/21619648
http://dx.doi.org/10.1186/1471-2180-11-120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125321/
https://www.ncbi.nlm.nih.gov/pubmed/21619648
http://dx.doi.org/10.1186/1471-2180-11-120

Ejemplares similares