Cell-free synthesis of a functional G protein-coupled receptor complexed with nanometer scale bilayer discs

BACKGROUND: G protein coupled receptors (GPCRs) represent the largest family of membrane proteins in the human genome and the richest source of targets for the pharmaceutical industry. A major limitation to characterizing GPCRs has been the difficulty in developing high-level heterologous expression...

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Detalles Bibliográficos
Autores principales: Yang, Jian-Ping, Cirico, Tatiana, Katzen, Federico, Peterson, Todd C, Kudlicki, Wieslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125327/
https://www.ncbi.nlm.nih.gov/pubmed/21605442
http://dx.doi.org/10.1186/1472-6750-11-57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125327/
https://www.ncbi.nlm.nih.gov/pubmed/21605442
http://dx.doi.org/10.1186/1472-6750-11-57

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