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Cell-free synthesis of a functional G protein-coupled receptor complexed with nanometer scale bilayer discs
BACKGROUND: G protein coupled receptors (GPCRs) represent the largest family of membrane proteins in the human genome and the richest source of targets for the pharmaceutical industry. A major limitation to characterizing GPCRs has been the difficulty in developing high-level heterologous expression...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125327/ https://www.ncbi.nlm.nih.gov/pubmed/21605442 http://dx.doi.org/10.1186/1472-6750-11-57 |