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Phosphoproteomic Profiling of In Vivo Signaling in Liver by the Mammalian Target of Rapamycin Complex 1 (mTORC1)

BACKGROUND: Our understanding of signal transduction networks in the physiological context of an organism remains limited, partly due to the technical challenge of identifying serine/threonine phosphorylated peptides from complex tissue samples. In the present study, we focused on signaling through...

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Detalles Bibliográficos
Autores principales: Demirkan, Gokhan, Yu, Kebing, Boylan, Joan M., Salomon, Arthur R., Gruppuso, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125343/
https://www.ncbi.nlm.nih.gov/pubmed/21738781
http://dx.doi.org/10.1371/journal.pone.0021729