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Sampling strategies for accurate computational inferences of gametic phase across highly polymorphic major histocompatibility complex loci

BACKGROUND: Genes of the Major Histocompatibility Complex (MHC) are very popular genetic markers among evolutionary biologists because of their potential role in pathogen confrontation and sexual selection. However, MHC genotyping still remains challenging and time-consuming in spite of substantial...

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Detalles Bibliográficos
Autores principales: Alcaide, Miguel, Rodríguez, Airam, Negro, Juan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126723/
https://www.ncbi.nlm.nih.gov/pubmed/21615903
http://dx.doi.org/10.1186/1756-0500-4-151