Adaptive molecular evolution of the Major Histocompatibility Complex genes, DRA and DQA, in the genus Equus

BACKGROUND: Major Histocompatibility Complex (MHC) genes are central to vertebrate immune response and are believed to be under balancing selection by pathogens. This hypothesis has been supported by observations of extremely high polymorphism, elevated nonsynonymous to synonymous base pair substitu...

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Detalles Bibliográficos
Autores principales: Kamath, Pauline L, Getz, Wayne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126738/
https://www.ncbi.nlm.nih.gov/pubmed/21592397
http://dx.doi.org/10.1186/1471-2148-11-128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126738/
https://www.ncbi.nlm.nih.gov/pubmed/21592397
http://dx.doi.org/10.1186/1471-2148-11-128

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