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Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1

BACKGROUND: The proteasome is a multi-subunit protein machine that is the final destination for cellular proteins that have been marked for degradation via an ubiquitin (Ub) chain appendage. These ubiquitylated proteins either bind directly to the intrinsic proteasome ubiqutin chain receptors Rpn10,...

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Detalles Bibliográficos
Autores principales: Gomez, Tara A, Kolawa, Natalie, Gee, Marvin, Sweredoski, Michael J, Deshaies, Raymond J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126750/
https://www.ncbi.nlm.nih.gov/pubmed/21627799
http://dx.doi.org/10.1186/1741-7007-9-33