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A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on (13)C mass isotopologue profiles under non-steady-state conditions

BACKGROUND: Stable isotope tracing is a powerful technique for following the fate of individual atoms through metabolic pathways. Measuring isotopic enrichment in metabolites provides quantitative insights into the biosynthetic network and enables flux analysis as a function of external perturbation...

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Detalles Bibliográficos
Autores principales: Moseley, Hunter NB, Lane, Andrew N, Belshoff, Alex C, Higashi, Richard M, Fan, Teresa WM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126751/
https://www.ncbi.nlm.nih.gov/pubmed/21627825
http://dx.doi.org/10.1186/1741-7007-9-37