Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4

BACKGROUND: Cyclin-dependent kinases 2, 4 and 6 (Cdk2, Cdk4, Cdk6) are closely structurally homologous proteins which are classically understood to control the transition from the G1 to the S-phases of the cell cycle by combining with their appropriate cyclin D or cyclin E partners to form kinase-ac...

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Detalles Bibliográficos
Autores principales: Warenius, Hilmar M, Kilburn, Jeremy D, Essex, Jon W, Maurer, Richard I, Blaydes, Jeremy P, Agarwala, Usha, Seabra, Laurence A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126777/
https://www.ncbi.nlm.nih.gov/pubmed/21668989
http://dx.doi.org/10.1186/1476-4598-10-72

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126777/
https://www.ncbi.nlm.nih.gov/pubmed/21668989
http://dx.doi.org/10.1186/1476-4598-10-72

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