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Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients

BACKGROUND: Identification of predictive markers of response to treatment is a major objective in breast cancer. A major problem in clinical sampling is the variability of RNA templates, requiring accurate management of tumour material and subsequent analyses for future translation in clinical pract...

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Detalles Bibliográficos
Autores principales: de Cremoux, Patricia, Valet, Fabien, Gentien, David, Lehmann-Che, Jacqueline, Scott, Véronique, Tran-Perennou, Carine, Barbaroux, Catherine, Servant, Nicolas, Vacher, Sophie, Sigal-Zafrani, Brigitte, Mathieu, Marie-Christine, Bertheau, Philippe, Guinebretière, Jean-Marc, Asselain, Bernard, Marty, Michel, Spyratos, Frédérique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126791/
https://www.ncbi.nlm.nih.gov/pubmed/21631949
http://dx.doi.org/10.1186/1471-2407-11-215