Visualization of Early Events in Acetic Acid Denaturation of HIV-1 Protease: A Molecular Dynamics Study

Protein denaturation plays a crucial role in cellular processes. In this study, denaturation of HIV-1 Protease (PR) was investigated by all-atom MD simulations in explicit solvent. The PR dimer and monomer were simulated separately in 9 M acetic acid (9 M AcOH) solution and water to study the denatu...

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Detalles Bibliográficos
Autores principales: Borkar, Aditi Narendra, Rout, Manoj Kumar, Hosur, Ramakrishna V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126794/
https://www.ncbi.nlm.nih.gov/pubmed/21738569
http://dx.doi.org/10.1371/journal.pone.0019830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126794/
https://www.ncbi.nlm.nih.gov/pubmed/21738569
http://dx.doi.org/10.1371/journal.pone.0019830

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