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Visualization of Early Events in Acetic Acid Denaturation of HIV-1 Protease: A Molecular Dynamics Study

Protein denaturation plays a crucial role in cellular processes. In this study, denaturation of HIV-1 Protease (PR) was investigated by all-atom MD simulations in explicit solvent. The PR dimer and monomer were simulated separately in 9 M acetic acid (9 M AcOH) solution and water to study the denatu...

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Detalles Bibliográficos
Autores principales:	Borkar, Aditi Narendra, Rout, Manoj Kumar, Hosur, Ramakrishna V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126794/ https://www.ncbi.nlm.nih.gov/pubmed/21738569 http://dx.doi.org/10.1371/journal.pone.0019830

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