Rescue of Photoreceptor Degeneration by Curcumin in Transgenic Rats with P23H Rhodopsin Mutation

The P23H mutation in the rhodopsin gene causes rhodopsin misfolding, altered trafficking and formation of insoluble aggregates leading to photoreceptor degeneration and autosomal dominant retinitis pigmentosa (RP). There are no effective therapies to treat this condition. Compounds that enhance diss...

Descripción completa

Detalles Bibliográficos
Autores principales: Vasireddy, Vidyullatha, Chavali, Venkata R. M., Joseph, Victory T., Kadam, Rajendra, Lin, Jonathan H., Jamison, Jeffrey A., Kompella, Uday B., Reddy, Geereddy Bhanuprakash, Ayyagari, Radha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126808/
https://www.ncbi.nlm.nih.gov/pubmed/21738619
http://dx.doi.org/10.1371/journal.pone.0021193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126808/
https://www.ncbi.nlm.nih.gov/pubmed/21738619
http://dx.doi.org/10.1371/journal.pone.0021193

Ejemplares similares